| 外燥对小鼠气道免疫分子影响的实验研究 |
| |
| 引用本文： | 张六通,丁建中,王明明,胡利群,王昌富,贺尚荣. 外燥对小鼠气道免疫分子影响的实验研究[J]. 中国中医药现代远程教育, 2011, 9(11): 159-160. DOI: 10.3969/j.issn.1672-2779.2011.11.107 |
| |
| 作者姓名： | 张六通 丁建中 王明明 胡利群 王昌富 贺尚荣 |
| |
| 作者单位： | 1. 湖北中医药大学,武汉,430061
2. 湖北长江大学医学院,荆州,434023 |
| |
| 基金项目： | 国家自然科学基金资助项目 |
| |
| 摘 要： | 目的动态观察外燥对小鼠气道液免疫分子的影响。方法 40只SPF级昆明小鼠随机分为常温常湿组(A组)、常温燥组(B组)、温燥组(C组)、凉燥组(D组),每组10只。处理后第6、12、18天检测各组气道液中分泌型IgA(SIgA)、IgG和肿瘤坏死因子(TNF-a)。结果与燥相关三个组第6～18天TNF-α、IgG同期下降,温燥组第6～18天TNF-a、IgG与SIgA均持续降低。结论再次证实,外燥伤肺耗津之时,可降低气道"纤毛-黏液毯"免疫御邪屏障,是外燥损伤"正气"为病之精细病机之一。
|
| 关 键 词： | 外燥 小鼠 气道液 免疫分子 |
Effects on the Resplratory Immunological Molecules of Mise in Outer-Dry |
| |
| Zhang Liutong,Ding Jianzhong,Wang Mingming,Hu Lin-qun,Wang Changfu,He Shangrong. Effects on the Resplratory Immunological Molecules of Mise in Outer-Dry[J]. Chinese Medicine Modern Distance Education of China, 2011, 9(11): 159-160. DOI: 10.3969/j.issn.1672-2779.2011.11.107 |
| |
| Authors: | Zhang Liutong Ding Jianzhong Wang Mingming Hu Lin-qun Wang Changfu He Shangrong |
| |
| Affiliation: | Zhang Liutong1,DIng Jianzhong2,Wang Mingming1,Hu Lin-qun2,Wang Changfu2,He Shangrong2(1.Hubei college of Traditional Chinese Medicine,Wuhan 430061,Chian,2..Medical shool of Yangtze University,Jinzhou 434023,China) |
| |
| Abstract: | Aim To investigate the effects on the immunological molecules of respiratory in Outer-Dry.Methods 40 kunming mice（SPF） were divided into four groups：group A（normal）,group B（normal temperature and Outer-Dry）,groupC（Warm-Dry）,group D（Cool-Dry）,10mices/group.SIgA、 IgG and Tumor Necrosis Factor-a（TNF-a）of mice＇respiratory were measured in day 6,12 and 18.Results Compared with group A,IgG-R and TNF-a of group B,C and D were reduced,SIgA,IgG and TNF-a of group C were noticeable weaked in day 6 to 18.Conlusion The results were repeated indicated that the remarkable injuring of immunological molecules of ＂respiratory mucus barrier＂were related with the mechanisms of Outer-Dry with disordering of＂secretion and the transport＂of＂lung-fluid＂. |
| |
| Keywords: | Outer-Dry Mice Respiratory mucus Immunological molecule |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
