| 齐拉西酮联合碳酸锂治疗双相障碍躁狂发作的对照研究 |
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| 引用本文： | 刘向阳,史建新,李云.齐拉西酮联合碳酸锂治疗双相障碍躁狂发作的对照研究[J].中国实用医药,2011,6(31):39-40. |
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| 作者姓名： | 刘向阳 史建新 李云 |
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| 作者单位： | 河南省驻马店市精神病医院,463000 |
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| 摘 要： | 目的观察齐拉西酮联合碳酸锂治疗双相障碍躁狂发作的临床疗效及安全性。方法将68例双相障碍躁狂发作患者随机分为两组,各34例,研究组口服齐拉西酮和碳酸锂,对照组口服碳酸锂治疗,观察6周。于治疗前及治疗后第2、4、6周末采用Beck-Rafaelsen躁狂量表(BRMS)评定临床疗效,以副反应量表(TESS)评定不良反应。结果在第2周末评分研究组比对照组有显著下降,在第6周末两组评分均显著下降,差异无统计学意义;两组不良反应发生差异无统计学意义。结论齐拉西酮联合碳酸锂治疗双相障碍躁狂发作起效快疗效好,不良反应轻,安全性高。
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| 关 键 词： | 齐拉西酮 碳酸锂 双相障碍 躁狂发作 |
A control study of ziprasidone vs.Lithium carbonate in the treatment of the therapy of bipolar disorder manic episode |
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| LIU Xiang-yang,SHI Jian-xin,LI Yun.A control study of ziprasidone vs.Lithium carbonate in the treatment of the therapy of bipolar disorder manic episode[J].China Practical Medical,2011,6(31):39-40. |
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| Authors: | LIU Xiang-yang SHI Jian-xin LI Yun |
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| Institution: | LIU Xiang-yang,SHI Jian-xin,LI Yun.Mental Hospital of Zhumadian City,Zhumadian 463000,China |
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| Abstract: | Objective To explore the efficacy and safety of quetiapine vs.Lithium carbonate in the treatment of bipolar disorder manic episode(BDME).Methods Sixty-eight BDME patients were randomly assigned to two groups of 34 ones each,research group took orally quetiapine and control group did lithium carbonate for 6 weeks.Clinical efficacies were assessed with the Beck-Rafaelsen Mania Scale(BRMS) and Treatment Emergent Symptom Scale(TESS) before treatment and at the end of the 2nd,4th and 6nd week.Results Score of st... |
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| Keywords: | Ziprasidone Lithium Bipolar disorder Manic episode |
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