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p27与卵巢癌
引用本文:姚军,于江,黄健. p27与卵巢癌[J]. 华夏医学, 2003, 16(1): 125-127
作者姓名:姚军  于江  黄健
作者单位:1. 桂林医学院附属医院妇产科,广西,桂林,541001
2. 桂林医学院生物工程研究所,广西,桂林,541004
基金项目:广西自然科学基金 (桂科自 0 2 2 90 5 7)
摘    要:p27是目前国内外研究得较多的一种CKIs,它以多种方式参与细胞周期的调控,最终抑制细胞的分裂和增殖,促进细胞的分化和凋亡。现就其与卵巢肿瘤的发生发展,预后,耐药及治疗的研究进展作一综述。

关 键 词:p27 细胞周期 调控 卵巢肿瘤
文章编号:1008-2409(2003)01-0125-03
修稿时间:2002-09-19

p27 and Ovarian Cancer
YAO Jun//The Affiliated Hospital of Guilin Medical College,Guilin ,China. p27 and Ovarian Cancer[J]. Acta Medicinae Sinica, 2003, 16(1): 125-127
Authors:YAO Jun//The Affiliated Hospital of Guilin Medical College  Guilin   China
Affiliation:YAO Jun//The Affiliated Hospital of Guilin Medical College,Guilin 541001,China
Abstract:p27 is one kind of cyclin dependent kinase,that has been studied intensively both in China and abroad p27 joins the regulation of cell cycle by several ways,and finally inhibits the cell proliferation and facilitates the differentiation and apoptosis of cells This article reviews the research progress on the relationship between p27 and the pathogenesis,development,prediction as well as treatment of ovarian carcinoma
Keywords:p27  cell cycle  regulation  ovarian carcinoma
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