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阿立哌唑与氯丙嗪治疗精神分裂症对照研究
引用本文:王刚平 颉瑞 裴根祥. 阿立哌唑与氯丙嗪治疗精神分裂症对照研究[J]. 精神医学杂志, 2005, 18(4): 250-251
作者姓名:王刚平 颉瑞 裴根祥
作者单位:甘肃省天水市精神病医院,741000
摘    要:目的 探讨阿立哌唑与氯丙嗪对首发精神分裂症患者的临床疗效及安全性。方法 72例精神分裂症患者随机分为两组,分别给予阿立哌唑与氯丙嗪,治疗8周,用阳性与阴性症状表(PANSS)和副反应量表(TESS)评定疗效和不良反应。结果 阿立哌唑组疗效优于氯丙嗪组(P〈0.05),阿立哌唑不良反应显著少于氯丙嗪(P〉0.05)。结论 阿立哌唑是一种安全有效的抗精神病药。

关 键 词:精神分裂症 阿立哌唑 氯丙嗪
文章编号:1009-7201(2005)-04-0250-02
收稿时间:2005-05-14
修稿时间:2005-05-14

A comparative study between aripiprazole and chlorpromazine in the treatment of schizophrenia
Wang GangPing;Jie Rui;Pei GenXiang. A comparative study between aripiprazole and chlorpromazine in the treatment of schizophrenia[J]. Journal of Psychiatry, 2005, 18(4): 250-251
Authors:Wang GangPing  Jie Rui  Pei GenXiang
Abstract:Objective To explore the clinical efficacy and side effects of aripiprazole and chlorpromazine in the treatment of first-episode schizophrenia. Methods A total of 72 schizophrenic inpatients were randomly divided into aripiprazole group or chlorpromazine group for 8 weeks. PANSS and TESS were used to evaluate the efficacy and side effects respectively. Results There was significant difference in effecacy between two groups. Aripiprazole had fewer side effects than chlorpromazine. Conclusion Aripiprazole is a safe and effective antipcychotic drug.
Keywords:Schizophrenia Aripiprazole Chlorpromazine
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