围生期女性盆底重塑

妊娠和分娩是导致盆底功能障碍性疾病（pelvic floor dysfunction，PFD）的根源。围生期是育龄女性生命周期中的一个特殊时期，机体各个系统代谢、功能等方面均受到影响发生改变。随着妊娠子宫的不断增大、盆底承受的压力逐渐增加，围生期的女性盆底组织也发生一系列重塑（remodeling）以维持盆腔脏器解剖位置及功能的稳定。一旦这种稳定状态失去平衡，就表现为盆底功能障碍。盆底组织的重塑贯穿于整个围生期，并存在着个体差异。对围生期女性盆底神经、肌肉和结缔组织的重塑过程做文献综述，为研究盆底功能障碍的发病机制及寻找更有效的PFD防治方法提供理论依据。

Female Pelvic Floor Remodeling in Perinatal Period

Pelvic floor dysfunction （PFD） is strongly correlated with pregnancy and childbirth. The mechanisms of pelvic floor injury leading to PFD are largely unknown. The female pelvic floor can undergo a series of remodeling to maintain the anatomic and functional stability. The pelvic floor remodeling contains nerve, muscle and connective tissue; it is also carried through the whole perinatal period and shows individual difference. Study of female pelvic floor remodeling is beneficial to demonstrating the pathogenesis of PDF and providing effective therapy.