牡蛎提取物软胶囊缓解体力疲劳功能研究

目的 研究牡蛎提取物软胶囊对缓解体力疲劳功能的效果。方法 ICR种雄性小鼠随机分为低、中、高剂量组和阴性对照组,剂量组分别灌胃给予0.30g/kg.bw、0.60g/kg.bw、1.80g/kg.bw的牡蛎提取物软胶囊内容物,阴性对照组给予食用植物油,连续灌胃30d后,对小鼠进行负重游泳试验、血清尿素、肝糖原和血乳酸测定。结果 高剂量组延长小鼠的负重游泳时间、提高肝糖原含量、降低小鼠血清尿素含量,与对照组比较有显著性差异 (P<0.05 )。结论 牡蛎提取物软胶囊具有缓解体力疲劳功能的作用。

Study on Effect of Oyster extract Soft Capsule on the Alleviating Physical Fatigue Function

Objective To study the Relieving Physical Fatigue effect of Oyster extract Soft Capsule. Methods Male ICR mice were divided into 4 groups randomly, including low-,medium- and high-dose Oyster extract soft capsule groups, negative control group. Male mice with the body weight of 18-22g were divided into four groups randomly, Mice in three dose groups were respectively intragastric adiministered 0.30, 0.60, 1.80g/kg.bw Oyster extract soft capsule and negative control group mice were intragastric adiministered edible vegetable oil for 30d. Loaned swimming time, serum urea content, liver glycogen and blood lactate content of mice were measured. Results Compared with negative control group, high dose group of Oyster extract Soft Capsule , the loaned swimming time and glycogen content significantly increased and blood urea level obviously decreased（P<0.05). Conclusion The study indicates that oyster extract soft capsule has significant anti-fatigue effect.