| 唐古特大黄提取物不同成分泻下作用的比较研究 |
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| 引用本文： | 李文渊,童丽,热增才旦,王海洁,李永平,金伟,屠鹏飞,格日力,. 唐古特大黄提取物不同成分泻下作用的比较研究[J]. 中国中药杂志, 2007, 32(2): 137-139 |
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| 作者姓名： | 李文渊 童丽 热增才旦 王海洁 李永平 金伟 屠鹏飞 格日力 |
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| 作者单位： | 1. 青海大学,医学院,中藏药研究中心,青海,西宁,81000
2. 北京大学,中医药现代化研究中心,北京,100083 |
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| 摘 要： | 目的：研究唐古特大黄提取物不同成分的泻下作用。方法：采用炭末推进方法、酚红排空方法进行肠推进实验,观察大黄提取物各成分(15 g·kg-1)对小鼠小肠推进和肠水分吸收、大鼠大肠运动的影响。结果：唐古特大黄提取物不同成分与对照组相比,对小鼠小肠推进和肠水分吸收、大肠推进作用均有显著性差异(P<0.01)；与大黄水煎液、醇提液相比,泻下活性存在一些差异。结论：唐古特大黄提取物不同成分均有显著的泻下作用,但与大黄水煎液和醇提液相比有一些差异。
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| 关 键 词： | 唐古特大黄 泻下作用 番泻苷 蒽醌苷 蒽醌苷元 |
| 文章编号： | 1001-5302（2007）02-0137-03 |
| 收稿时间： | 2006-06-20 |
| 修稿时间： | 2006-06-20 |
Comparative study on purgative activity of different extracts from Rheum tanguticum |
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| LI Wen-yuan; TONG Li; RE Zeng-caidan; WANG Hai-jie; LI Yong-ping; JIN Wei; TU Peng-fei; GE Ri-li. Comparative study on purgative activity of different extracts from Rheum tanguticum[J]. China Journal of Chinese Materia Medica, 2007, 32(2): 137-139 |
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| Authors: | LI Wen-yuan TONG Li RE Zeng-caidan WANG Hai-jie LI Yong-ping JIN Wei TU Peng-fei GE Ri-li |
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| Abstract: | Objective: To observe purgative activity of different constituents extracted from Rheum tanguticum.Method: The purgative effects of different constituents(sennidine,anthraquinone and anthraquinone aglycome) from R.tanguticum were studied by injecting charcoal ink into the intestines and by colorimetric method of phenol red.Result: As comparaed with control group,the purgatire effects of the different constituents extracted from R.tanguticum had significant differences,and however,had somewhat difference compared with aqueous decoction and ethanol extract groups.Conclusion: The different extracts from R.tanguticum all had the purgative activity. |
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| Keywords: | Rheum tanguticum purgative activity sennidine anthraquinone anthraquinone aglycone |
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