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Struktur-Wirkungs-Beziehungen bei Histaminanaloga, 24. Mitt. Absolute Konfiguration und histaminartige Wirkung der Enantiomere von 4-(2-Aminopropyl)-5-methyl-imidazol
Authors:Siegfried Schwarz  Walter Schunack
Abstract:Structure-Activity Relationships of Histamine Analogues, XXIV: Absolute Configuration and Histamine-Type Activity of the Enantiomers of 4-(2-Aminopropyl)-5-methylimidazole The resolution of 4-(2-aminopropyl)-5-methylimidazole (1) , the determination of the absolute configuration and the histamine-type activity of the enantiomers on the guinea pig ileum (H1) and atrium (H2) are reported.
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