Phenolic glycosides from the filamentous fungus Acremonium sp. BCC 14080 |
| |
| Authors: | Bunyapaiboonsri Taridaporn Yoiprommarat Seangaroon Khonsanit Artit Komwijit Somjit |
| |
| Affiliation: | National Center for Genetic Engineering and Biotechnology (BIOTEC), Thailand Science Park, Klong 1, Klong Luang, Pathumthani, Thailand. taridaporn@biotec.or.th |
| |
| Abstract: | New phenolic mono- and digalactopyranosides (1 and 2), their aglycone KS-501a (3), and a new phenolic 4-O-methylglucopyranoside (4) were isolated from the filamentous fungus Acremonium sp. BCC 14080. Structures of these compounds were elucidated by extensive MS and NMR spectroscopic analyses. Compound 1 displayed anti-HSV-1 activity with an IC(50) value of 7.2 microM. Compound 3 exhibited activity against Plasmodium falciparum K1 with an IC(50) value of 9.9 microM. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
