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Prevalence of familial hypercholesterolaemia in patients presenting with premature acute coronary syndrome |
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| Institution: | 1. Department of Cardiology, Centre de Référence des Cardiomyopathies et des Troubles du Rythme Cardiaque Héréditaires ou Rares, UVSQ, Ambroise-Paré Hospital, AP–HP, 92100 Boulogne-Billancourt, France;2. Inserm U-1018, CESP, Épidémiologie Clinique, UVSQ, 94805 Villejuif, France;3. Public Health Department, UVSQ, Ambroise-Paré Hospital, AP–HP, 92100 Boulogne-Billancourt, France;4. Department of Geriatrics, Ambroise Paré Hospital, AP–HP, UVSQ, 92100 Boulogne-Billancourt, France;5. Département Hospitalier d’Épidémiologie et de Santé Publique, GHU Paris-Saclay, Hôpital Raymond-Poincaré, AP–HP, 92380 Garches, France;6. Local Health Insurance, Hauts de Seine, 92000 Nanterre, France;7. Laboratory of Biochemistry and Molecular Genetics, Université Paris-Saclay, Ambroise-Paré Hospital, AP–HP, 92100 Boulogne-Billancourt, France;8. Unité de Génétique Médicale, Centre de Référence des Maladies Cardiaques Héréditaires ou Rares, Ambroise-Paré Hospital, AP–HP, 92100 Boulogne-Billancourt, France;9. Sorbonne Université, INSERM, UMR_S 1166 and ICAN Institute for Cardiometabolism and Nutrition, 75013 Paris, France;10. Department of Nephrology, UVSQ, Ambroise-Paré Hospital, AP–HP, 92100 Boulogne-Billancourt, France | |
| Abstract: | Central illustration. Prevalence of familial hypercholesterolaemia (FH) among young adults with myocardial infarction (MI) (n = 457) and in the general control population (CARVAR 92 cohort) (n = 9900), and cardiovascular risk factors associated with premature acute MI.  | |
| Keywords: | Familial hypercholesterolaemia Dutch Lipid Clinic Network score Acute myocardial infarction Epidemiology Hypercholestérolémie familiale Score de Dutch Infarctus du myocarde aigu Épidémiologie ACS"} {"#name":"keyword" "$":{"id":"kw0050"} "$$":[{"#name":"text" "_":"acute coronary syndrome CI"} {"#name":"keyword" "$":{"id":"kw0060"} "$$":[{"#name":"text" "_":"confidence interval CVD"} {"#name":"keyword" "$":{"id":"kw0070"} "$$":[{"#name":"text" "_":"cardiovascular disease DLCN"} {"#name":"keyword" "$":{"id":"kw0080"} "$$":[{"#name":"text" "_":"Dutch Lipid Clinic Network FH"} {"#name":"keyword" "$":{"id":"kw0090"} "$$":[{"#name":"text" "_":"familial hypercholesterolaemia LDL-C"} {"#name":"keyword" "$":{"id":"kw0100"} "$$":[{"#name":"text" "_":"low-density lipoprotein cholesterol MI"} {"#name":"keyword" "$":{"id":"kw0110"} "$$":[{"#name":"text" "_":"myocardial infarction OR"} {"#name":"keyword" "$":{"id":"kw0120"} "$$":[{"#name":"text" "_":"odds ratio PCSK9"} {"#name":"keyword" "$":{"id":"kw0130"} "$$":[{"#name":"text" "_":"proprotein convertase subtilisin/kexin 9 | |
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