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Development of a compact MRI system for measuring the trabecular bone microstructure of the finger.
Authors:Nachiko Iita  Shinya Handa  Sadanori Tomiha  Katsumi Kose
Affiliation:Institute of Applied Physics, University of Tsukuba, Tsukuba, Japan.
Abstract:A compact MRI system for measuring the trabecular bone (TB) microstructure of the finger using a high-field-strength (1.0T) permanent magnet was developed. The entire system was installed in a 0.6 mx1.2 m space. One male and 36 female subjects participated in the imaging experiments. The TB of the distal phalanx of the middle finger was imaged at a voxel resolution of (160 microm)3 using a three-dimensional (3D) driven equilibrium spin-echo (SE) imaging sequence (imaging time=approximately 14 min). The image data sets obtained yielded two distinct peaks for the bone and marrow in image intensity histograms when no motion was present. The structural parameters obtained through 3D image analysis show that this compact system is potentially useful for evaluating bone quality.
Keywords:osteoporosis  trabecular bone  compact MRI  permanent magnet  finger
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