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Long-term effect of bone marrow transplantation in adult-onset adrenoleukodystrophy |
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| Authors: | T. Hitomi T. Mezaki H. Tomimoto A. Ikeda S. Shimohama T. Okazaki T. Uchiyama H. Shibasaki |
| Affiliation: | Department of Neurology, Kyoto University Hospital, Kyoto, Japan. hitomi46@kuhp.kyoto-u.ac.jp |
| Abstract: | We report a long-term outcome of motor function in a patient with adult-onset adrenoleukodystrophy after bone marrow transplantation (BMT). Clinically motor function gradually improved and became almost normal in 2 years after BMT. Serial transcranial magnetic stimulation showed gradual improvement of central motor conduction until 1 year after BMT, and then it became stable. Central motor conduction time and motor threshold were useful for monitoring the central motor function in this patient. |
| Keywords: | adrenoleukodystrophy bone marrow transplantation central motor conduction long-term follow-up transcranial magnetic stimulation |