Pubertal growth and growth hormone secretion |
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Authors: | P M Martha E O Reiter |
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Affiliation: | Tufts University School of Medicine, Boston, Massachusetts. |
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Abstract: | A dramatic increase in linear growth velocity, often referred to as the pubertal growth spurt, is a central feature of pubertal development. Despite the existence of numerous investigative attempts, a precise understanding of the hormonal events subserving this process has proved elusive. Nevertheless, evidence has gradually accumulated that indicates that sex steroid-induced modulation of growth hormone secretion is a central and critical feature of the pubertal growth spurt. As a result, disorders of either growth hormone or sex steroid hormone production may result in clinical growth disorders during puberty. |
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