Thyroid function at birth in infants of 30 to 45 weeks' gestation. |
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| Authors: | T H Oddie D A Fisher B Bernard R W Lam |
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| Institution: | 1. Department of Radiology, Harbor General Hospital, UCLA School of Medicine, Torrance, Torrance, Calif. USA;2. Department of Pediatrics, Harbor General Hospital, UCLA School of Los Angeles, Calif. USA;3. Department of Medicine, Harbor General Hospital, UCLA School of Medicine, Torrance, Torrance, Calif. USA;4. Los Angeles County Women''s Hospital, Los Angeles, Calif. USA |
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| Abstract: | Serum T4 was measured in cord blood of 2,683 infants of gestational ages 30 to 45 weeks and birth weights of 1,460 to 5,250 gm. In addition, serum TBG was measured in 180, and serum TSH in 125 of these infants. Mean serum T4 increased with gestational age from 9.4 microng/dl at 30 weeks to 11.7 at 45 weeks. TBG varied from 3.1 to 11.4 mg/dl but showed no correlation with gestational age. There was a positive correlation between T4 and TBG. Serum TSH levels showed a significant negative correlation with gestational age, decreasing from 15 micronU/ml at 30 weeks to 7 micronU/ml at 45 weeks, while the serum T4/TSH ratio increased from 0.6 to 1.6. The results indicate that cord, T4 varies mainly with TBG, and to a lesser extent with gestational age. |
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| Keywords: | Reprint address: Harbor General Hospital Building A-17 1000 West Carson St Torrance CA 90509 |
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