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Disseminated Adenovirus Infection in Cancer Patients Presenting with Focal Pulmonary Consolidation |
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| Authors: | Yeon Joo Lee Paola Palomino-Guilen N Esther Babady Daryl M Lamson Kirsten St George Yi-Wei Tang Genovefa A Papanicolaou |
| Institution: | aInfectious Disease, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, USA;bClinical Microbiology Service, Memorial Sloan-Kettering Cancer Center, New York, New York, USA;cWeill Medical College, Cornell University, New York, New York, USA;dNew York State Department of Health, Albany, New York, USA |
| Abstract: | We report disseminated adenovirus (ADV) infection in four adult cancer patients presenting with focal pulmonary consolidation. In all cases, ADV was recovered from respiratory specimens and ADV viremia (>1 × 105 copies/ml) was determined by a quantitative PCR assay. Despite antiviral therapy, 3 (75%) patients died. ADV should be considered as a possible cause of severe pneumonia in immunosuppressed patients. |
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