Antibiotic Resistance Genes in the Bacteriophage DNA Fraction of Human Fecal Samples |
| |
| Authors: | Pablo Quirós Marta Colomer-Lluch Alexandre Martínez-Castillo Elisenda Miró Marc Argente Juan Jofre Ferran Navarro Maite Muniesa |
| |
| Affiliation: | aDepartment of Microbiology, University of Barcelona, Barcelona, Spain;bServei de Microbiologia, Hospital de la Santa Creu i Sant Pau, Institut d''Investigació Biomèdica Sant Pau, Barcelona, Spain |
| |
| Abstract: | A group of antibiotic resistance genes (ARGs) (blaTEM, blaCTX-M-1, mecA, armA, qnrA, and qnrS) were analyzed by real-time quantitative PCR (qPCR) in bacteriophage DNA isolated from feces from 80 healthy humans. Seventy-seven percent of the samples were positive in phage DNA for one or more ARGs. blaTEM, qnrA, and, blaCTX-M-1 were the most abundant, and armA, qnrS, and mecA were less prevalent. Free bacteriophages carrying ARGs may contribute to the mobilization of ARGs in intra- and extraintestinal environments. |
| |
| Keywords: | |
|
|
