局部晚期鼻咽癌放射治疗联合化疗的研究进展

临床Ⅲ ～Ⅳ期鼻咽癌占鼻咽癌的的大多数，根治性放疗联合化疗的综合治疗是局部晚期鼻咽癌治疗的基石，现有的证据表明，同步放化疗是中国局部晚期鼻咽癌标准治疗方法，但放化疗的最佳组合方案仍未确定。本文就这方面的研究进展作一综述。

Progression of chemotherapy in combination with radiotherapy for locally advanced nasopharyngeal carcinoma

The majority of patients with nasopharyngeal carcinoma will present with stage Ⅲ and/or Ⅳ in China. The regimens of curative radiotherapy with chemotherapy are mainstay for locally advanced nasopharyngeal carcinoma because of locoregional relapse and distant metastases. There is evidence to suggest that concurrent chemoradiotherapy for locally advanced nasopharyngeal carci- noma would be standard strategy in mainland China, but scheduling of chemotherapy and radiotherapy is unanswered. This article reviews the recent literature and the relevant issues concerning the role of chemotherapy in combination with radiotherapy in the treatment of patients with locoregionally advanced nasopharvngeal carcinoma.