Effect of acoustic tumor extension into the internal auditory canal on distortion-product otoacoustic emissions

We studied the effects on distortion-product otoacoustic emissions (DPOAEs) of internal auditory canal (IAC) extension of acoustic neuromas (ANs) with the hypothesis that cochlear patterns of DPOAEs would be more commonly observed when the IAC was completely filled with tumor because of direct tumor involvement of either the inner ear or its blood supply. In a retrospective analysis of 86 patients with surgically proven ANs, DPOAEs were classified as having cochlear or noncochlear patterns on the basis of comparisons with the behavioral pure tone thresholds. The results of behavioral audiometry and DPOAEs were compared with the extension of the tumor into the IAC, which was categorized as full or partial. Of the 86 patients, 58 had tumors with full IAC extension, and 28 had tumors with partial IAC involvement. Cochlear patterns of DPOAEs were found in 55.2% of the tumors in the full IAC group and in 71.4% of those in the partial IAC group (not statistically different). It was concluded that the extent of IAC involvement by ANs was not significantly related to the negative effects of the tumor on cochlear function as represented by DPOAEs.