Exogenous lipoid pneumonia following ingestion of liquid paraffin |
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Authors: | Ohwada Akihiko Yoshioka Yasuko Shimanuki Yuri Mitani Keiko Kumasaka Toshio Dambara Takashi Fukuchi Yoshinosuke |
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Institution: | Department of Respiratory Medicine, Juntendo University School of Medicine, Tokyo. |
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Abstract: | An asymptomatic patient with exogenous lipoid pneumonia (ELP) due to silent aspiration of liquid paraffin ingested as a lubricant was diagnosed by bronchoalveolar lavage (BAL). BAL fluid separated into oily upper phase and lower aqueous phase spontaneously. Microscopic analysis of BAL cells revealed the presence of lipid-laden alveolar macrophages. Classic histochemical staining and electron microscope examination indicated that neutral lipid was dominant but phospholipid was also present in the lipid-laden macrophages. Together with the history of ingestion of liquid paraffin, we identified that the ingested liquid paraffin was the origin of the neutral lipid in the lipid-laden macrophages observed in the BAL fluid. |
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