Phosphorylcholine determinants in six pneumococcal capsular polysaccharides detected by monoclonal antibody. |
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| Authors: | U B S rensen, R Agger, J Bennedsen, J Henrichsen |
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| Affiliation: | U B Sørensen, R Agger, J Bennedsen, and J Henrichsen |
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| Abstract: | The presence of phosphorylcholine in pneumococcal capsular polysaccharides was examined by using monoclonal antiphosphorylcholine antibody. Of the 83 known capsular types of Streptococcus pneumoniae, 6 types, viz., 24A, 27, 28F, 28A, 32F, and 32A, gave a positive capsular reaction (quellung) which could be inhibited by phosphorylcholine. The capsular polysaccharides of these six types, therefore, contain phosphorylcholine. |
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