白木香叶化学成分的研究

目的:研究白木香叶的化学成分,为白木香的综合利用提供依据.方法:采用硅胶柱色谱、Sephadex LH-20柱色谱、重结晶等方法进行分离纯化,运用NMR,Ms等波谱学方法进行结构鉴定.结果:从白木香叶中分离鉴定了13个化合物,分别为7-羟基-5,4'-二甲氧基.黄酮(1),洋芹素-7,4'-二甲醚(2),木犀草素-7,3',4'一三甲醚(3),异紫堇啡碱(4),对羟基苯甲酸(5),正三十二(烷)醇(6),正三十一烷(7),α-豆甾醇(8),表木栓醇(9),木栓烷(10),木栓酮(11),芫花素(12),5,4'-二羟基_7,3'-二甲氧基黄酮(13).结论:化合物4为首次从该属中分离得到,化合物1,6～11,13为首次从该植物中分离得到.

Studies on chemical constituents of leaves of Aquilaria sinensis

Objective: To investigate the chemical constituents of the leaves of Aquilaria sinensis, and provide a certain of basis for the comprehensive uses of the plant of A. sinensis.  Method: The chemical constituents were isolated by various column chromatographic method. The structures were identified by spectral analyses of NMR, MS, et al.  Result: Thirteen compounds were isolated and identified as 7 hyroxy 5, 4′ dimethoxy flovone (1), 5 hydroxy 7, 4′ dimethoxy flavone (2), luteolin 7 3′,4′ trimethyl (3), isocorydine (4), 4 hydroxybenzoic acid (5), triacontenoic (6), hentriacontane (7), α stigmasterol (8), epifriedelanol (9), friedelan (10), friedelin (11), genkwanin (12), 5,  4′ dihyroxy 7, 3′ dimethoxy flovone (13).  Conclusion: Compound 4 was obtained from this genus for the first time,compounds 1, 6 11, 13 were obtained from this species for the first time.