Relationship between expression of nm23 protein and clinical morphological factors and content of plasminogen activation system components in tumors of patients with gastric cancer

Immunohistochemical studies revealed a relationship between the expression of nm23 protein in gastric cancer cells and some parameters characterizing plasminogen activation system and clinical morphological factors. Expression of nm23 in the cytoplasm was detected almost 3-fold more often than in the nuclei; cytoplasmic expression more strictly correlated with patient’s age, tumor location, and its histological structure than nuclear expression. __________ Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 143, No. 6, pp. 678–681, June, 2007