骨组织工程基质材料的现状及展望

通过阐述理想骨组织工程细胞外基质材料的要求，并总结生物类材料、生物陶瓷类材料、聚合物类材料和复合类材料在骨组织工程中用作细胞外基质材料的优缺点，认为理想的骨组织工程细胞外基质材料最好由生物陶瓷类材料、人工合成聚合物类材料或天然聚合物类材料组成，并含有最佳的生长因子缓释系统的多孔三维立体泡沫，这种复合型细胞外基质材料的研制是骨组织工程研究中十分重要而迫切的任务。

The Current Situation and Future of Extracellular Matrix Materials for Bone Tissue Engineering

The requirements of ideal extracellular matrix materials for bone tissue engineering were stated, and the advantages and disadvantages of bioceramics, biodegradable synthetic polymers and natural polymers were analyzed. Based on these, we highlight a point that the ideal extracellular matrix materials for bone tissue engineering should be made up of bioceramics materials, synthetic polymers or natural polymers. These materials should possess a morphological structure of three dimensional foam and have a self mediated drug delivery system of bone growth factors. The design and manufacture of such compound extracellular matrix materials for bone tissue engineering is a very important and urgent challenge.