脑卒中患者真菌性医院感染分析

目的研究脑卒中患者真菌性医院感染发病率及其危险因素,以采取有效措施。方法回顾性分析2002年9月~2005年9月,我院神经内科收治的脑卒中患者3 027例的有关临床资料。结果脑卒中患者真菌性医院感染发生率为3.24%;以下呼吸道和口腔感染最常见,分别占67.2%和21.1%;感染菌株主要是念珠菌属占96.7%;高龄、昏迷、广谱抗生素应用及时间、长住院日、糖尿病、吞咽困难、低蛋白血症等与真菌性医院感染密切相关。结论念珠菌属是真菌性医院感染的主要病原菌;要积极控制相关危险因素,预防真菌性医院感染的发生。

Nosocomial Fungal Infection in Cerebral Apoplectic Patients: A Clinical Analysis

OBJECTIVE To investigate and control the risk factors about nosocomial fungal infection in cerebral apoplectic patients. METHODS To study retrospectively 3027 hospitalized patients with cerebral apoplexia in our hospital from Sep 2002 to Sep 2005. RESULTS The incidence of nosocomial fungal infection was 3.24% in all(3 027 cases).Nosocomial fungal infection occurred mainly in lower respiratory tract(67.2%) and oral cavity(21.1%),the main pathogens of nosocomial fungal infection were Candida spp(96.7%).Developments of nosocomial fungal infections were closely related with aging,time of antibiotics therapy,coma,bed-days,diabetes mellitus,difficulties in swallowing,and hypoalbuminemia. CONCLUSIONS The rate of nosocomial fungal infections is higher in cerebral apoplectic patients with aging coma,long bed-days,diabetes mellitus,difficulties in swallowing,hypoalbuminemia,and receiving broad-spectrum antimicrobial agents therapy.Candida spp are the main pathogens of nosocomial fungal infections.We must take some measures to control the risk factors mentioned above and prevent nosocomial fungal infections.