| 鼠原发性三叉神经痛下丘脑β内啡肽含量测定 |
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| 引用本文： | 刘红娟,王文宇,孙宏晨. 鼠原发性三叉神经痛下丘脑β内啡肽含量测定[J]. 中华口腔医学杂志, 2005, 40(2): 154-155 |
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| 作者姓名： | 刘红娟 王文宇 孙宏晨 |
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| 作者单位： | 1. 130021,长春,吉林省人民医院口腔科
2. 吉林大学口腔医学院口腔病理科 |
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| 摘 要： | 目的 检测鼠三叉神经痛脑组织中β内啡肽含量及其生理作用。方法 取Wister大鼠 37只,分为实验组 20只,生理盐水组 10只,空白对照组 7只。建立鼠三叉神经痛实验动物模型,采用放射免疫测定β内啡肽含量。结果 实验组明显低于生理盐水组和空白对照组,P<0 01。结论 脑组织中β内啡肽含量明显降低是引起鼠原发性三叉神经痛的重要原因之一。
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| 关 键 词： | 鼠 原发性三叉神经痛 下丘脑 β内啡肽 含量 测定 |
| 修稿时间： | 2004-10-29 |
Determination of β-endorphin in hypothalamus of rat with primary trigeminal neuralgia |
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| LIU Hong-juan,WANG Wen-yu,SUN Hong-chen. Determination of β-endorphin in hypothalamus of rat with primary trigeminal neuralgia[J]. Chinese journal of stomatology, 2005, 40(2): 154-155 |
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| Authors: | LIU Hong-juan WANG Wen-yu SUN Hong-chen |
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| Affiliation: | Department of Oral Medicine, People's Hospital of Jilin Province, Changchun 130021, China. |
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| Abstract: | OBJECTIVE: To determine the level and the role of beta-endorphin in hypothalamus of rat with trigeminal neuralgia. METHODS: The animal model of primary trigeminal neuralgia in rat was established, the contents of beta-endorphin were measured by radioimmunoassay techniques. RESULTS: The beta-endorphin of hypothalamus in experimental group was significantly lower than other groups (P < 0.01). CONCLUSIONS: Beta-endorphin may play important roles in primary trigeminal neuralgia. |
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| Keywords: | Trigeminal neuralgia Neurotransmitters Hypothalamus Beta-endorphin |
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