| 中药注射剂不良反应发生的原因分析 |
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| 引用本文： | 朱立勤,徐彦贵,王屏,陈媛媛,高仲阳. 中药注射剂不良反应发生的原因分析[J]. 中国药房, 2007, 18(3): 215-218 |
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| 作者姓名： | 朱立勤 徐彦贵 王屏 陈媛媛 高仲阳 |
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| 作者单位： | 1. 天津市第一中心医院,天津市,300192
2. 天津医科大学药学院,天津市,300070 |
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| 摘 要： | 目的了解中药注射剂不良反应(ADR)发生的原因。方法通过跟踪随访和病例回顾的方式对对照组(100例)及ADR组(93例),在药物、患者、处方及护理因素方面进行单因素和多因素分析。结果与结论中药注射剂致不良反应的主要原因为给药剂量过大、联合用药、输液距配液时间过长、用药前没有进行肝肾功能检查、适应证不合理、说明书中用法用量不详细、没有药理作用的说明。改进处方及护理行为对提高临床用药的安全性具有重要意义。
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| 关 键 词： | 中药注射剂 不良反应 原因 分析 |
| 文章编号： | 1001-0408（2007）03-0215-04 |
| 收稿时间： | 2006-06-08 |
| 修稿时间： | 2006-09-18 |
Analysis on Causes of ADR Associated with Traditional Chinese Medicine Injections |
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| ZHU Liqin,XU Yangui,WANG Ping,CHEN Yuanyuan,GAO Zhongyang. Analysis on Causes of ADR Associated with Traditional Chinese Medicine Injections[J]. China Pharmacy, 2007, 18(3): 215-218 |
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| Authors: | ZHU Liqin XU Yangui WANG Ping CHEN Yuanyuan GAO Zhongyang |
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| Affiliation: | The First Central Hospital of Tianjin, Tianjin 300192, China;School of Pharmacy, Tianjin Medical University, Tianjin 300070, China |
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| Abstract: | OBJECTIVE:To comprehend the causes for adverse drug reactions (ADR)associated with the traditional Chinese medicine injections in order to improve therapeutic safety.METHODS:Through tracking visits and retrospective study of patient cases,100 control cases and 93 ADR cases are analyzed in terms of medicine,patient,prescribing and nursing,both by single-factor and multi-factor approach.RESULTS:The main causes of ADR associated with traditional Chinese medicine injections are:overdosing,combined administration of drugs,longer-than-required time gap between dispensing and transfusion,failure to do pre-dosing liver or kidney function checkup,irrelevance of indication,lack of detailed instruction about way of administration and dosing,and lack of remarks on pharmacological action.CONCLUSION:It’s vitally important to improve prescribing and nursing behaviors for the sake of enhanced safety of clinical use of drugs. |
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| Keywords: | Traditional Chinese Medicine Injections ADR Cause Analysis |
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