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Lymphoplasmacyte-rich meningioma with atypical invasive nature
Authors:Nohara Hidenori  Furuya Kazuhide  Kawahara Nobutaka  Iijima Akira  Yako Kyoko  Shibahara Junji  Kirino Takaaki
Institution:Department of Neurosurgery, University of Tokyo Hospital, Tokyo, Japan.
Abstract:A 12-year-old boy presented with a lymphoplasmacyte-rich (LPR) meningioma in the posterior fossa. The tumor was subtotally removed. Histological examination showed the tumor had invaded the normal brain tissue despite its benign grade in the World Health Organization classification. The Ki-67 staining index using MIB-1 monoclonal antibody was relatively high. (18)F-2-fluoro-2-deoxy-D-glucose positron emission tomography revealed high uptake in the tumor. These findings indicate the atypical nature of LPR meningioma.
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