Transplanted adipose-derived stem cells delay D-galactose-induced aging in rats |
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| Authors: | Chun Yang Dongfei Li Zhongqiu Wen Huiying Yang Meichun Yu Hui Tao Rongmei Qu Yikuan Du Yong Huang Ou Sha Jingxing Dai Lin Yuan |
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| Affiliation: | Chun Yang1,Dongfei Li1,Zhongqiu Wen1,Huiying Yang1,Meichun Yu1,Hui Tao1,Rongmei Qu1,Yikuan Du2,Yong Huang3,Ou Sha4,Jingxing Dai1,Lin Yuan1 1Department of Anatomy,Southern Medical University,Guangzhou 510515,Guangdong Province,China 2Department of Orthopaedics,Linyi Traditional Chinese Medical Hospital,Linyi 276000,Shandong Province,China 3Department of Traditional Chinese Medicine,China 4School of Biomedical Sciences,Chi... |
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| Abstract: | To investigate the effects of allogeneically transplanted, adipose-derived stem cells in aging rats, in the present study, we established a rat model of subacute aging using continuous subcutaneous injections of D-galactose. Two weeks after the adipose-derived stem cells transplantations, serum superoxide dismutase activity was significantly increased, malondialdehyde content was significantly reduced, hippocampal neuronal degeneration was ameliorated, the apoptotic index of hippocampal neurons was decrease... |
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| Keywords: | adipose-derived stem cell transplantation stem cells fasciology fascial anatomy anti-aging |
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