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口服普萘洛尔治疗婴幼儿血管瘤的临床观察
引用本文:林晓斌,蔡湘娜,纪影畅,李吉林,郑练. 口服普萘洛尔治疗婴幼儿血管瘤的临床观察[J]. 汕头大学医学院学报, 2013, 26(1): 33-34,37
作者姓名:林晓斌  蔡湘娜  纪影畅  李吉林  郑练
作者单位:1. 汕头大学医学院第一附属医院小儿外科,广东汕头,515041
2. 汕头大学医学院第一附属医院整形外科,广东汕头,515041
3. 汕头大学医学院第一附属医院心血管内科,广东汕头,515041
基金项目:广东省医学科学技术研究基金资助项目(B2012252)
摘    要:目的:探讨小剂量普萘洛尔治疗婴幼儿血管瘤的疗效和安全性。方法:血管瘤患儿随机分为治疗组(30例。口服普萘洛尔0.5~2mg.kg-1.d-1))及对照组(30例。口服维生素C0.5~2mg.kg-1.d-1),疗程均1~9个月。结果:治疗组显效9例,有效19例,无效2例,有效率93.3%;对照组显效1例,有效8例,无效21例,有效率30.0%(P<0.05)。治疗组心动过缓2例,食欲下降2例;结论:普萘洛尔治疗婴幼儿血管瘤疗效显著,不良反应少,安全性较高,可作为婴幼儿血管瘤的一线用药。

关 键 词:普萘洛尔  血管瘤  婴幼儿

The Clinical Observation on Infantile Hemangioma Treated with Propranolol
LIN Xiao-bin , CAI Xiang-na , JI Ying-chang , LI Ji-lin , ZHENG Lian. The Clinical Observation on Infantile Hemangioma Treated with Propranolol[J]. Journal of Shantou University Medical College, 2013, 26(1): 33-34,37
Authors:LIN Xiao-bin    CAI Xiang-na    JI Ying-chang    LI Ji-lin    ZHENG Lian
Affiliation:1(1 Department of Pediatric Surgery,The First Affiliated Hospital,Shantou University Medical College,Shantou 515041,China,2 Department of Plastic Surgery,The First Affiliated Hospital,Shantou University Medical College,Shantou 515041,China,3 Department of Cardiovascular Medicine,The First Affiliated Hospital,Shantou University Medical College,Shantou 515041,China)
Abstract:Objective:To explore the efficacy and safety of propranolol in the treatment of infantile hemangioma.Methods:A total of 60 infants with hemangioma was classified into treatment group(taken orally propranolol 0.5 ~ 2.0 mg·kg-1.d-1)and control group(taken orally Vitamin C 0.5 ~ 2.0 mg·kg-1.d-1).The course was 1 to 9 months.Results:In the treatment group,there were 9 cases with marked effect,19 cases with effective results,2 cases with no-effect,and the efficiency was 93.3.In the control group,the excellent result was one case,8 cases with effective results,21 cases with no-effect,and the efficiency was 30.0%(P0.05).The tachycardia and anorexia were found,each 2 cases in the treatment group.Conclusion:Propranolol is effective and safety as first-line treatment for infantile hemangioma.
Keywords:propranolol  hemangioma  infantile
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