Die Gicht als Systemerkrankung |
| |
Authors: | Dr. A.-K. Tausche B. Manger U. Müller-Ladner B. Schmidt |
| |
Affiliation: | 1. Medizinische Klinik und Poliklinik III, Abteilung Rheumatologie, Universit?tsklinikum Carl Gustav Carus, Fetscherstr. 74, 01307, Dresden, Deutschland 2. Medizinische Klinik 3, Universit?t Erlangen-N??rnberg, Erlangen, Deutschland 3. Lehrstuhl f??r Innere Medizin mit Schwerpunkt Rheumatologie, Justus-Liebig Universit?t Giessen, Kerckhoff-Klinik Bad Nauheim, Bad Nauheim, Deutschland 4. Zentrum Innere Medizin, Abteilung Nephrologie, Kliniken der Medizinischen Hochschule Hannover, Hannover, Deutschland
|
| |
Abstract: | Of all inflammatory rheumatic diseases gout has the highest prevalence. Patients with intermittent acute gout attacks are usually treated by primary care physicians. However, in cases of insufficient long-term control of serum uric acid levels, complications or atypical clinical manifestations may necessitate consultation with a rheumatologist in the further course of the disease. An oligoarticular or polyarticular presentation can give rise to the initial suspicion of rheumatoid or psoriatic arthritis. In these cases a careful clinical work-up supported by laboratory and imaging investigations is necessary and synovial fluid analysis is usually required. As in other rheumatic diseases extra-articular manifestations are of utmost importance for morbidity and mortality. Gout is a complex metabolic and inflammatory disease and besides articular symptoms the renal and cardiovascular effects of hyperuricemia are particularly relevant for the overall prognosis. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|