Polycystic Liver Disease and Liver Transplantation: Single-Institution Experience |
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Authors: | B Taner DL Willingham WR Hewitt HP Grewal JH Nguyen CB Hughes |
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Institution: | Department of Transplantation Mayo Clinic Florida, Jacksonville, Florida |
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Abstract: | Adult polycystic liver disease (PLD) can cause massive hepatomegaly leading to pain, caval obstruction, and hemorrhage. Many surgical techniques including aspiration, fenestration, and resection have been used to treat PLD. In addition to substantial morbidity and mortality, conservative surgery may have limited success, and palliation may be temporary. With improved results of liver transplantation, it has become the definitive treatment for PLD. We retrospectively reviewed our experience in patients with PLD between 1998 and 2007. Thirteen patients underwent liver only or liver-kidney transplantation. All surgical procedures were performed with preservation of the recipient inferior vena cava and without venovenous bypass (piggyback technique). Our patients experienced a high rate of perioperative morbidity. However, long-term patient and graft survival were excellent. |
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