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2008~2009年中山地区医院病原菌耐药性分析及其对策
引用本文:黎颖然,刘锐锋,卢荣枝. 2008~2009年中山地区医院病原菌耐药性分析及其对策[J]. 现代食品与药品杂志, 2011, 0(11)
作者姓名:黎颖然  刘锐锋  卢荣枝
作者单位:中山市人民医院药学部;
基金项目:中山市卫生局科研项目(编号:2010015)
摘    要:目的分析2008~2009年度中山地区3家综合医院临床分离的病原菌种类、构成比以及耐药性特点。方法收集临床送检各类培养标本,采用全自动细菌鉴定仪进行细菌鉴定,用NCCLS推荐的K-B法进行药物敏感试验,并对特殊耐药菌进行鉴定。结果各年度均以革兰阴性杆菌为主,2008~2009年度大肠埃希菌、铜绿假单胞菌、克雷伯菌属、鲍曼不动杆菌等常见革兰阴性杆菌对亚胺培南、阿米卡星、哌拉西林/他唑巴坦等抗菌药物的耐药率较低。金黄色葡萄球菌和肠球菌等革兰阳性球菌对万古霉素、利奈唑烷等具有高度的敏感性。结论 2008~2009年临床标本送检情况与病原菌分布基本一致,应提高临床标本送检率,加强实验室特殊耐药菌监测,合理使用抗生素,以减缓耐药株的蔓延,减少二重感染机会。

关 键 词:细菌耐药性  抗菌药物  革兰阴性菌  革兰阳性菌  

Analysis and Countermeasures of Bacterial Resistance of Clinical Isolates from Hospital in 2008-2009 Zhongshan Area
LI Ying-ran,LIU Rui-feng,LU Rong-zhi. Analysis and Countermeasures of Bacterial Resistance of Clinical Isolates from Hospital in 2008-2009 Zhongshan Area[J]. JOurnal of Modern Food and Pharmaceuticals, 2011, 0(11)
Authors:LI Ying-ran  LIU Rui-feng  LU Rong-zhi
Affiliation:LI Ying-ran,LIU Rui-feng,LU Rong-zhi(Zhongshan People's Hospital,Zhongshan,Guangdong 528400,China)
Abstract:Objective To investigate the drug resistance of clinical isolates from 3 general hospitals in Zhangshan area from 2008 to 2009.Methods Various clinical cultures were collected,and automated bacterial identification system was used for bacteria identification.Drug susceptibility was tested by K-B method which recommended by NCCLS.The special resistant bacterial were identified.Results Gram negative bacilli were mainly caused respiratory tract or urinary tract infection.During 2008 to 2009,drug sensitivity te...
Keywords:bacterial resistance  anti-bacterial agents  gram-negative bacilli  gram-positive bacilli  
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