| 三七微粉与普通粉中有效成分的含量和溶出度比较 |
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| 引用本文： | 谢瑞芳,;周昕,;周端,;楼丹飞. 三七微粉与普通粉中有效成分的含量和溶出度比较[J]. 上海中医药杂志, 2009, 0(10): 79-81 |
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| 作者姓名： | 谢瑞芳, 周昕, 周端, 楼丹飞 |
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| 作者单位： | [1]上海中医药大学附属龙华医院药剂科,上海200032; [2]上海中医药大学附属龙华医院高血压病研究室,上海200032 |
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| 基金项目： | 上海市引进技术的吸收与创新计划资助项目（06YY-16） |
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| 摘 要： | 目的比较三七微粉（20μm）和普通粉（粗粉、中粉、细粉、极细粉）的含量和溶出度。方法以三七皂苷R1和人参皂苷Rg1为指标成分，采用高效液相色谱法测定三七微粉和普通粉的含量和溶出度。结果中粉和细粉中三七皂苷R1和人参皂苷Rg1的含量和溶出速度、累积溶出量最好。结论在含量和溶出度方面，三七微粉不比普通粉有优势。
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| 关 键 词： | 三七 微粉 普通粉 溶出度 高效液相 |
Comparison of Content and Dissolution Rate Between Norm Powder and Micro-powder of Panax notoginseng |
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| Affiliation: | XIE Rui-fang ZHOU Xin ZHOU Duan LOU Dan-fei (Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine) |
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| Abstract: | Objective To compare the content and dissolution rate between norm powder（ coarse powder, mediate powder, fine powder and super fine powder） and micro-powder（20μm）. Methods Notoginsenside R1 and ginsenoside Rgl were respectively analyzed by high performance liquid chromatograph （HPLC）. Results The dissolution rate of mediate powder（65-100 mesh） and fine powder （100-200 mesh） was higher, and the content and total dissolved amount were larger. Conclusion In content and dissolution rate, micro-powders have no significant superiority. |
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| Keywords: | Panax notoginseng micro-powder norm powder dissolution rate HPLC |
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