银丹心脑通软胶囊对腔隙性脑梗死患者血液流变学及血脂的影响

目的 探讨腔隙性脑梗死患者血液流变学和血脂指标的变化及银丹心脑通软胶囊对其的影响. 方法 检测62例腔隙性脑梗死患者血液流变学和血脂指标,并与50例健康老年人进行比较:62例腔隙性脑梗死患者中50例于银丹心脑通软胶囊治疗45 d后再次检测血液流变学和血脂指标,观察银丹心脑通软胶囊的治疗作用. 结果腔隙性脑梗死患者血液流变学指标均较健康老年人高,比较差异有统计学意义(P＜0.05);血三酰甘油、总胆固醇、低密度脂蛋白胆固醇均较健康老年人高,比较差异有统计学意义(P＜0.05).经银丹心脑通软胶囊治疗后,腔隙性脑梗死患者血液流变学和血脂指标均较治疗前有明显改善,比较差异有统计学意义(P＜0.05). 结论 腔隙性脑梗死患者存在血液流变学和血脂指标的明显异常,银丹心脑通软胶囊可改善老年腔隙性脑梗死患者的血液流变学及血脂异常.

Effects of Yindanxinnaotong capsule on hemorrheology indexes and blood lipid levels in elderly patients with lacunar infarction

Objective To investigate the effects of Yindanxinnaotong capsule on hemorrheology indexes and blood lipid levels in elderly patients with lacunar infarction (LI).Methods The hemorrheology indexes and blood lipid levels were measured in 62 elderly patients with LI, and then,compared with those of 50 healthy subjects. The hemorrheology indexes and lipid levels were re-measured to assess the therapeutic effect of Yindanxinnaotong capsule in 50 patients 45 d after the treatment. Results The hemorrheology indexes and the levels of total cholesterol, triglyceride, and low-density lipoprotein cholesterol in patient group were significantly higher than those in healthy control group before the treatment (P＜0.05). The hemorrheology indexes and blood lipid levels after the treatment with Yindanxinnaotong capsule in patient group were significantly improved as compared with those before treatment (P＜0.05). Conclusion The obvious abnormalities of hemorrheology indexes and blood lipid levels are found in aged patients with LI and Yindanxinnaotong capsule can improve these abnormalities.