| Abstract: | In carcinoma of the urinary bladder bone metastasis is rare. Ewing
(1) stated that metastases though uncotmnon m malignant papilloma uf
the urinary bladder had been observed in liver, lung, pleura, kidney,
and inguinal and axillary lymph nodes. Bone metastasis was not men
tioned. Colston (2) conceded that mctastasis to the bone from carcinoma
of the urinary bladder did undoubtcdLy occur, but in his experience it
was rare. Cabot (3) believed that mclas:asis in carcinoma of the urinary
bladder was a late event, and thu it occurred primarily in the regional
lymph nodes. Widespread mctastases to r!:e honcs, lungs, liver and pcri-
toneum, were less frequent, and the bony structures of the pelvis and
lumbar spine were probably afTected by retrograde lymphatic invasion
and not distribution through the blood stream. Moore (4) in a study of
65 cases of metastatic growth in bone, found none primary in v.he
urinary bladder. Spooncr (5) analyzerl 163 cases of carcinoma of the
urinary bladder in Mayo Clinic and listed the order of frequcncy of
metastasis as follows: liver, lung, suprarenal gIand, kidney, heart,
spleen, pancrcas, thyroid gland, stomach and bonc. |
