介入超声下聚桂醇硬化剂对肝囊肿患者肝功能与安全性的影响

目的研究介入超声下聚桂醇硬化剂对肝囊肿患者肝功能与安全性的影响。方法收集2018年11月至2019年10月收治的94例肝囊肿患者,按照随机数字表法分为对照组和观察组各47例。对照组实施超声介入穿刺注射无水乙醇硬化剂治疗,观察组实施超声介入穿刺注射聚桂醇硬化剂治疗。将两组的临床效果、治疗相关指标、囊肿体积、症状积分、肝功能指标、不良反应发生情况进行对比。结果观察组患者的临床总有效率高于对照组,差异均有统计学意义(P<0.05);观察组患者的治疗时间、治疗后住院时间短于对照组,液体抽取量多于对照组,治疗费用少于对照组,治疗后3个月、6个月时的囊肿体积小于对照组,差异均有统计学意义(P<0.05);观察组患者治疗后的症状积分、不良反应发生率低于对照组,差异有统计学意义(P<0.05);观察组患者治疗后的ALB高于对照组,治疗后的TBIL、ALT、AST、ALP水平均低于对照组,差异有统计学意义(P<0.05)。结论对肝囊肿患者实施超声介入穿刺注射聚桂醇硬化剂治疗具有较高的有效性和安全性,能有效缩小囊肿体积,促进临床症状和肝功能改善,适合在临床中推广应用。

Effect of lauryl alcohol sclerotherapy on liver function and safety in patients with hepatic cyst under interventional ultrasound

Objective To study the effect of lauryl alcohol sclerotherapy on liver function and safety in patients with hepatic cyst under interventional ultrasound.Methods 94 hepatic cyst patients from Nov.2018 to Oct.2019 were included in the study,and they were divided into two groups according to the random number table method.47 cases in the control group were treated with ultrasound intervention and injection of anhydrous ethanol sclerotherapy,and 47 cases in the observation group were treated with ultrasound intervention injection of lauryl alcohol sclerotherapy.The clinical effect,treatment related indicators,cyst volume,symptom score,liver function index and adverse reactions were compared between the two groups.Results The clinical total effective rate of the observation group was higher than that of the control group,the difference was statistically significant(P<0.05);the treatment time and hospitalization time of the observation group were shorter than those of the control group,the liquid extraction volume was more than the control group,the treatment cost was less than the control group,and the cyst volume at 3 months and 6 months after treatment was smaller than that of the control group,the difference was statistically significant(P<0.05).The symptom score and incidence of adverse reactions in the observation group were lower than those in the control group(P<0.05);the ALB in the observation group was higher than that in the control group,and the levels of TBIL,ALT,AST and ALP after treatment were lower than those in the control group(P<0.05).Conclusion Ultrasound interventional puncture injection of lauryl alcohol sclerotherapy for patients with liver cyst has high efficacy and safety,can effectively reduce the cyst volume,promote the improvement of clinical symptoms and liver function,and is suitable for clinical application.