健康成人胼胝体核磁共振影像解剖学研究

目的 探讨健康成人胼胝体各部分径值及与年龄的相关性,为相关疾病的诊断提供正常胼胝体数据. 方法 选择120例健康成人自愿者(男、女各半),行头部T1加权序列MR扫描.在正中矢状面上测量胼胝体的膝部、压部、体部的宽度以及胼胝体长度与高度. 结果 120例健康成人胼胝体膝部、压部、体部的宽度以及胼胝体长度与高度分别为(11.35±2.16) mm、(9.97±2.09)mm、(5.93±1.32)mm、(73.33±3.77)mm、(25.34±3.01)mm.经统计学分析发现健康成人腩随年龄的增加胼胝体的膝部、乐部、体部的宽度逐渐减小,而胼胝体的长度与高度随年龄增加而增加,呈显著相关性(P<0.05).胼胝体形态随年龄的增长而呈弓背样增高. 结论 胼胝体的各部分径值及形态与年龄密切相关.

Magnetic resonance imaging-bused anatomical characterization of the corpus eallosum in healthy adults

Objective To investigate the age- and gender-related differences in the anatomical dimensions in healthy Chinese adults based on magnetic resonance imaging (MRI) and provide reference data on normal corpus callosum for diagnosis of related diseases. Methods Sixty male and 60 female healthy Chinese volunteers were recruited in this study. Tl-weighted MR images of the head were acquired using a 1.5-Tesla Siemens scanner. In the median sagittal image, the width of the genu, splenium and body of the corpus callosum were measured, and the length and the height of corpus callosum were also estimated. Results The average width of the genu, splenium, and body of the corpus callosum and the length and height of the corpus callosum in these 120 volunteers were 11.35±2.16 mm, 9.97±2.09 mm, 5.93±1.32 mm, 73.33±3.77 mm and 25.34±3.01 mm, respectively. Statistical analysis indicated that the measured values of each part of the corpus callosum decreased with age whereus the length and height of the corpus callsum increased with age. The arch of the corpus callosum also tended to increase with age. Conclusion The anatomical dimensions and shape of the corpus canosum undergo alterations in close relation with age.