慢性肾脏病并发急性肾损伤98例临床分析

目的探讨慢性肾脏病患者急性肾损伤的致病因素及临床治疗要点。方法回顾本院收治、并发急性肾损伤的98例慢性肾脏病患者，对其发病原因、临床治疗疗效和预后做综合分析。结果C／A的发病与年龄密切相关，多发于老年人，98例患者中，年龄〉60岁患者占70．4％（69例）；且不同年龄段患者的诱发因差异有统计学意义（P〈0．05），老年人的诱发因主要是感染、心血管疾病和药物，而青壮年则以原发病进展为主要因素；高发C／A的基础性肾病主要是高血压肾病、糖尿病肾病及肾小球肾炎。结论C／A的致病因在不同年龄段有不同的侧重点，可做针对性预防；准确寻找致病因和及时对症治疗是提高临床疗效的关键。

Chronic kidney disease and acute Kidney injury, 98 cases of clinical analysis

Objective Acute kidney injury in patients with chronic kidney disease （CKD） to explore the pathogenic factors and clinical treatment of points. Methods Review the patients with acute renal failure, 98 cases of chronic kidney disease patients, the disease causes, the clinical curative effect and prognosis do comprehensive analysis. Results C/A disease and age was closely related to multiple in the elderly, 98 cases of patients, age 〉 sixty years old patient 70. 4% （n = 69） ; And different age patients induced due to signifi- cant difference （P 〈 0.05）, the elderly was mainly induced by infection, cardiovascular diseases and drugs, and prime criterion with the primary disease progress as the main factors; C/A high basic kidney disease was mainly hypertension nephropathy, diabetic nephropathy and glomerular inflammation. Conclusion C/A be- cause pathogenic in different age paragraph have different emphasis, may do targeted prevention; Accurate and timely for pathogenic for symptomatic treatment is the key to improve the clinical effect.