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Nitroxide Synthase Activity as a Marker of Early Stages of Experimental Cartilage Dysmetabolism |
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| Authors: | A. V. Cherepovskii A. I. Dubikov S. V. Nikulin L. A. Belogolovykh E. E. Medved' |
| Affiliation: | Vladivostok State Medical Institute. |
| Abstract: | Time course of nitroxide synthase activity in the knee joint cartilage was studied in animals with experimental anterior instability of the knee joint. A significant increase in nitroxide synthase activity in chondrocytes was paralleled by a progressive decrease in glycosaminoglycan content in the cartilaginous matrix and subsequent destruction of the cartilage cytoarchitectonics. |
| Keywords: | nitrogen oxide nitroxide synthase cartilage osteoarthrosis |
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