Etiología y sensibilidad antimicrobiana en las infecciones urinarias bajas de la embarazada en España

Introduction

To improve antibiotic use in the treatment of urinary tract infections during pregnancy, knowledge of the most frequent pathogens and their susceptibilities is required.

Methods

Between march and july 2004, a prospective multicenter study was conducted in 15 national microbiology laboratories. The laboratories used their standard methods to process the samples.

Results

Pregnancy or non-pregnancy was recorded in only 1521 women; of these, 150 women were pregnant. The most frequent pathogen in pregnant women was Escherichia coli (54.6%), followed by Streptococcus agalactiae (24.3%). Isolation of gram positive strains (32.2%) was significantly more frequent in pregnant women (p < 0.001). The susceptibility rates of E.coli were 98.8% for fosfomycin, 96.2% for cefixime, and 97.6% for nitrofurantoin; these rates were lower for ampicillin (41.6%).

Conclusions

E.coli is the main uropathogen during pregnancy, because of the materno-fetal complications of urinary tract infections during pregnancy, alternative antibiotics should be used to reduce the high resistance to antibiotics that are useful in neonatal sepsis.