Using and interpreting cost-effectiveness acceptability curves: an example using data from a trial of management strategies for atrial fibrillation |
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| Authors: | Elisabeth Fenwick Deborah A Marshall Adrian R Levy Graham Nichol |
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| Affiliation: | (1) Public Health and Health Policy, University of Glasgow, Glasgow, UK;(2) Department of Clinical Epidemiology and Biostatistics, McMaster University and Centre for Evaluation of Medicines,St. Joseph's Hospital, Hamilton, ON, Canada;(3) Department of Health Care and Epidemiology, University of British Columbia, Vancouver, BC, Canada;(4) Harborview Center for Prehospital Emergency Care, University of Washington, Seattle, USA |
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| Abstract: | Background The cost-effectiveness acceptability curve (CEAC) is a method for summarizing the uncertainty in estimates of cost-effectiveness. The CEAC, derived from the joint distribution of costs and effects, illustrates the (Bayesian) probability that the data are consistent with a true cost-effectiveness ratio falling below a specified ceiling ratio. The objective of the paper is to illustrate how to construct and interpret a CEAC. |
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