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超声回声跟踪技术评价不伴危险因素的糖耐量减低患者颈动脉僵硬度改变
引用本文:张辉,赵素玲,李鹏,胡兆霆,周荣刚,吕素琴. 超声回声跟踪技术评价不伴危险因素的糖耐量减低患者颈动脉僵硬度改变[J]. 中国医学影像技术, 2012, 28(2): 282-285
作者姓名:张辉  赵素玲  李鹏  胡兆霆  周荣刚  吕素琴
作者单位:1. 中山大学附属第三医院超声科中山大学超声与介入治疗研究所,广东广州,510630
2. 南方医科大学附属第三医院超声科,广东广州,510360
基金项目:广东省医学科研基金(A2008391)。
摘    要:目的 使用超声回声跟踪技术评估不伴有危险因素的糖耐量减低(IGT)患者的颈动脉僵硬度.方法 选择明确诊断为IGT的患者50例(IGT组),另选年龄、性别等相匹配的50名健康志愿者作为对照组,采用超声回声跟踪技术测定两组颈动脉僵硬度.结果 IGT组的颈动脉硬化度、弹性系数、顺应性、脉搏波传导速度均较对照组增高[硬化度:9.93±3.35 vs 8.40±2.58;弹性系数:135.63±51.85 vs 110.19±35.68;顺应性:(0.86±0.31)mm2/kPa vs (0.71±0.24)mm2/kPa;脉搏波传导速度:(7.32±1.93)m/s vs (6.37±1.37)m/s],而两组膨大系数差异无统计学意义[(4.46±8.22)% vs (3.81±12.24)%].结论 应用超声回声跟踪技术能准确测量糖耐量减低患者颈总动脉的僵硬度参数,无创地早期评价其血管病变程度,为临床治疗提供客观依据.

关 键 词:颈动脉  动脉粥样硬化  糖耐量实验  回声跟踪
收稿时间:2011-07-27
修稿时间:2011-09-27

Ultrasound echo-tracking in assessing carotid artery stiffness of impaired glucose tolerance patients without risk factors
ZHANG Hui,ZHAO Su-ling,LI Peng,HU Zhao-ting,ZHOU Rong-gang and LV Su-qin. Ultrasound echo-tracking in assessing carotid artery stiffness of impaired glucose tolerance patients without risk factors[J]. Chinese Journal of Medical Imaging Technology, 2012, 28(2): 282-285
Authors:ZHANG Hui  ZHAO Su-ling  LI Peng  HU Zhao-ting  ZHOU Rong-gang  LV Su-qin
Affiliation:Department of Ultrasound, the Third Affiliated Hospital, Sun Yat-sen University, Institute of Diagnostic and Interventional Ultrasound, Sun Yat-sen University, Guangzhou 510630, China;Department of Ultrasound, the Third Affiliated Hospital of Southern Medical University, Guangzhou 510360, China;Department of Ultrasound, the Third Affiliated Hospital of Southern Medical University, Guangzhou 510360, China;Department of Ultrasound, the Third Affiliated Hospital of Southern Medical University, Guangzhou 510360, China;Department of Ultrasound, the Third Affiliated Hospital of Southern Medical University, Guangzhou 510360, China;Department of Ultrasound, the Third Affiliated Hospital, Sun Yat-sen University, Institute of Diagnostic and Interventional Ultrasound, Sun Yat-sen University, Guangzhou 510630, China
Abstract:Objective To measure carotid artery stiffness with ultrasound echo-tracking(ET),so as to assess the atherosclerotic changes of carotid artery in impaired glucose tolerance(IGT) patients without risk factors.Methods Fifty IGT patients(IGT group) and 50 healthy volunteers(control group) with matched age,gender and other general information underwent ultrasound ET,and carotid artery stiffness was measured.Results Stiffness(β),pressure strain elastic modulus(Ep),artery compliance(AC),pulse wave velocity(PWVβ) were higher in IGT group than those in control group(β: 9.93±3.35 vs 8.40±2.58,Ep: 135.63±51.85 vs 110.19±35.68,AC: [0.86±0.31]mm2/kPa vs [0.71±0.24]mm2/kPa,PWVβ: [7.32±1.93] m/s vs [6.37±1.37]m/s),whereas augmentation index(AI) was not significantly different between them([4.46±8.22]% vs [3.81±12.24]%).Conclusion Ultrasound ET can accurately assess early carotid artery stiffness of impaired glucose tolerance patients without risk factor,therefore providing evidence for clinical managements.
Keywords:Carotid arteries  Atherosclerosis  Glucose tolerance test  Echo-tracking
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