| 正交实验优化牛蒡子的提取工艺 |
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| 引用本文： | 卢来春,张蓉,周世文,蒋学文.正交实验优化牛蒡子的提取工艺[J].儿科药学杂志,2007,13(1):10-11. |
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| 作者姓名： | 卢来春 张蓉 周世文 蒋学文 |
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| 作者单位： | 第三军医大学新桥医院,重庆,400037;第三军医大学新桥医院,重庆,400037;第三军医大学新桥医院,重庆,400037;第三军医大学新桥医院,重庆,400037 |
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| 摘 要： | 目的:优选牛蒡子乙醇提取的最佳工艺.方法:采用L9(34)正交试验筛选醇提工艺条件,用HPLC法测定牛蒡苷的含量.结果:牛蒡子的最佳醇提条件为:乙醇浓度70%,加8倍溶剂量,回流3次,回流时间1h.结论:采用本工艺牛蒡子的活性成分牛蒡苷提取率达95.43%,工艺可行.
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| 关 键 词： | 牛蒡子 牛蒡苷 正交设计 |
| 文章编号： | 1672-108X（2007）01-0010-02 |
| 收稿时间： | 2006-11-02 |
| 修稿时间： | 2006-12-05 |
Optimization of the technology of extracting chemical constituents from fructus arctii by orthogonal experimental design |
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| LU Lai-chun, ZHANG Rong, ZHOU Shi-wen, et al.Optimization of the technology of extracting chemical constituents from fructus arctii by orthogonal experimental design[J].Journal of Pediatric Pharmacy,2007,13(1):10-11. |
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| Authors: | LU Lai-chun ZHANG Rong ZHOU Shi-wen |
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| Abstract: | Objective:To optimize the technology of extracting chemical constituents from fructus arctii.Methods: HPLC was used to analyze the content of Arctinin,and the L_9(34) orthogonal experimental design was used to optimize the conditions of the ethanol extraction technology.Results: The conditions of the ethanol extraction technology of extracting the constituents from Fructus arctii were 70 % ethanol, 1 hour of reflux,8-fold solvent and 3 times of extraction.Conclusions: With the extraction rate of arctiin as 95.43%,the optimized technology is stable and practical and worthy of a trial in pharmaceutical production. |
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| Keywords: | Fructus arctii Arctinin Orthogonal experimental design |
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