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系列乳癖合剂治疗实验性豚鼠乳腺增生病的研究
作者姓名:郑陆辛  纪福  陈华元  钱静  陈钢  李瑞琴  陈瑾
作者单位:1. 扬州大学医学院,江苏,扬州,225001
2. 昆山市红十字医院,江苏,昆山,215300
基金项目:江苏省社会发展科技项目(BS98335)
摘    要:观察系列乳癖合对豚鼠乳腺增生动物模型的影响,阐明其作用机理。方法以苯甲酸雌二醇造成豚鼠乳腺增生病模型,分别灌服天冬素片水溶液及择期灌乳系列乳癖合剂,观察其乳腺腺大小变化、组织病理变化、血中性激素含量。结论系列乳癖合剂能降低实验性豚鼠血中雌二醇含量。

关 键 词:系列乳癖合剂  乳腺增生  中医药疗法
文章编号:1000-5005(2000)01-0028-02
修稿时间:1999年10月11

Study on a Series of Rubi Mixtures in Treating Experimental Mastoplasia of Guinea-pigs
Authors:Zhen Luxin  Ji Fu  Chen Huayuan  Qian Jing  Chen Gang  Li Ruiqin  Chen Jin
Abstract:OBJECT:To observe the influence of a series of Rubi mixtures on guinea-pig model with mastoplasia, so as to elucidate their mechanisms of action. METHOD:The model was made by estradiol benzoate, the solution of aspartic acid and a series of Rubi mixtures were taken in different time by these animals respectively, the size of mammary gland, histopathological change and the content of blood sex hormone were observed. RESULT: This series of mixtures could alleviate the experimental mastoplasia of guinea-pigs, subtract the increased value of breast and reduce blood estradiol content, so their effects was better than that of aspartic acid. CONCLUSIONA: series of Rubi mixtures could reduce the blood estradiol content of experimental guinea-pig.
Keywords:a series of Rubi mixtures  mastoplasia  animal model  administration in different time  estradiol
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