钩枝藤茎枝生物碱类成分的研究

 目的对钩枝藤茎、枝的化学成分进行研究。方法采用氧化铝柱色谱,硅胶柱色谱,Sephadex LH-20凝胶柱色谱进行分离,通过理化和波谱分析鉴定结构。结果分离并鉴定了7生物碱个化合物。分别为ancistrobertsonine B(1),an- cistrotectorine(2),(1S,3S)-5-(4,5-二甲氧基-2-甲基萘-1-基)-6,8-二甲氧基-1,3-二甲基-1,2,3,4-四氢异喹啉(3),(1S,3R)-5-(4,5-二甲氧基-2-甲基萘-1-基)-6,8-二甲氧基-1,3-二甲基-1,2,3,4-四氢异喹啉(4),ancistro- cline(5),ancistrocladinine(6),hamatinine(7)。结论化合物1,3,4,6,7均为首次从该植物中分离得到。

Studies on Constituents of the Stems and Branches of Ancistrocladus tectorius

OBJECTIVE To study the chemical constituents of the stems and branches of Ancistrocladus tectorius.METHODS The constituents were isolated and purified by chromatography on aluminium oxide,silica gel and Sephadex LH-20 column.Their structures were identified by physicochemical properties and spectral analysis.RESULTS Seven alkaloids compounds were isolated and identified as ancistrobertsonine B(1),ancistrotectorine(2),(1S,3S)-5-(4,5-dimethoxy-2-methyl-naphthalen-1-yl)-6,8- dimethoxy-1,3-dimethyl-1,2,3,4-tetrahydruisoquinoline(3),(1S,3R)-5-(4,5-dimethoxy-2-methylnaphthalen-1-yl)-6,8- dimethoxy-1,3-dimethyl-1,2,3,4-tetrahydroisoquinoline(4),ancistrocline(5),ancistrocladinine(6),hamatinine(7). CONCLUSION Compounds 1,3,4,6 and 7 were isolated from this plant for the first time.