创伤后横纹肌溶解症致急性肾功能衰竭的连续性肾脏替代治疗

目的 提高创伤后横纹肌溶解所致急性肾功能衰竭的诊治水平.方法 回顾性分析20例创伤后横纹肌溶解症致急性肾功能衰竭患者的临床表现、实验室检查和治疗.其中9例给予连续性肾脏替代治疗(CRRT)与11例未做CRRT者作对照.结果 9例创伤后横纹肌溶解症致急性肾功能衰竭给予CRRT,除2例死亡外,7例患者均获得临床治愈;11例未做CRRT者5例死亡,5例继发慢性肾功能不全,1例患者临床治愈.结论 早期诊断、连续性肾脏替代治疗、充分水化、支持治疗是提高治愈率的有效措施,出现肾功能不全须尽早进行连续性肾脏替代治疗.

Continuous renal replacement therapy for rhabdomyolysis-induced acute renal failure following trauma

Objective To improve diagnose and therapy of post-traumatic acute renal failure induced by rhabdomyolysis. Methods A total of 20 patients with post-traumatic acute renal failure induced by rhabdomyolysis were analyzed retrospectively in aspects of clinical manifestation, laboratory examination and treatment. Of all, there were 9 patients treated with continuous renal replacement therapy (CRRT), while the other 11 were set as control, receiving no CRRT. Results After treatment with CRRT, 7 patients obtained clinical curing, with 2 deaths. As for control patients, there were 5 patients with secondary chronic renal insufficiency, 1 with clinical curing and 5 deaths. Conclusions Early diagnosis, CRRT, sufficient hydration, hematedialysis and supportive treatment are key points to improve the cure rate. It is important to apply CRRT for patients with renal inadequacy.