Macroscopic, histologic, histochemical, immunohistochemical, and ultrastructural features of mesothelioma |
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Authors: | Hammar Samuel P |
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Affiliation: | a Diagnostic Specialties Laboratories, Bremerton, Washington, USA |
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Abstract: | Mesotheliomas are uncommon neoplasms that arise from the cells forming the serosal membranes of the body cavities. Approximately 90-95% of mesotheliomas arise in the pleural cavity and 5-10% in the peritoneal cavity. Rare mesotheliomas arise in the pericardium and in the tunica vaginalis. Unlike many neoplasms, mesotheliomas grow in a diffuse distribution and tend to encase the organs in the various body cavities. A combination of histochemical, immunohistochemical, and ultrastructural features are often necessary to accurately diagnose mesotheliomas. These techniques are highlighted in this review article on mesothelioma. |
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Keywords: | electron microscopic histochemical histologic immunohistochemical macroscopic mesothelioma |
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