强离子隙等指标在 ICU 中的应用探讨 |
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引用本文: | 张忠源,胡望平,池细弟,叶桂云,徐尚华,张永平,叶龙飞.强离子隙等指标在 ICU 中的应用探讨[J].国际检验医学杂志,2014,0(13):1683-1685. |
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作者姓名: | 张忠源 胡望平 池细弟 叶桂云 徐尚华 张永平 叶龙飞 |
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作者单位: | 张忠源 (福建医科大学附属南平第一医院检验科,福建南平,353000); 胡望平 (南京军区福州总医院生化科,福建福州,350025); 池细弟 (福建医科大学附属南平第一医院检验科,福建南平,353000); 叶桂云 (福建医科大学附属南平第一医院检验科,福建南平,353000); 徐尚华 (福建医科大学附属南平第一医院检验科,福建南平,353000); 张永平 (福建医科大学附属南平第一医院检验科,福建南平,353000); 叶龙飞 (福建医科大学附属南平第一医院检验科,福建南平,353000); |
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基金项目: | 福建省卫生厅青年科研基金项目(2011-01-50)。 |
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摘 要: | 目的:探讨继 pH、阴离子隙(AG)后的第三代方程式产生的强离子隙(SIG)在危重症患者中的临床应用价值。方法在测定血气、血生化结果基础上,应用 Stewart-Figge 方法学的方程式计算 SIG。结果(1)危重症患者各组 K+、Na+、HCO3-、AG、pH、PO43-、ALB、SIG 及 Cr 水平与对照组比较差异有统计学意义(P <0.05)。(2)死亡组与非死亡组 SIG 均值的比值为3.04,差别最大,两组间 AG 和 Cr 的比值次之。结论SIG 作为一个新的指标在与其他生化、血气指标如 HCO3-、AG、pH、PO43-、Cr 及乳酸联合应用时,能更好地反映危重病患者的酸碱紊乱情况,对预测疾病发展趋势有较强的指示作用。
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关 键 词: | 强离子隙 重症监护病房 血气分析 乳酸 |
Application of strong ion gap and other indicators in ICU |
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Institution: | Zhang Zhongyuan,Hu Wangping,Chi Xidi,Ye Guiyun,Xu Shanghua,Zhang Yongping,Ye Longfei ( 1. Department of Clinical Labarotory ,Affiliated Nanping First Hospital, Fujian Medical University, Nanping , Fujian 35300, China 2. Department of Biochemistry, Fuzhou General Hospital. of Nanjing Military Region, Fuzhou, Fujian 350025, China) |
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Abstract: | Objective To investigate the clinical application value of strong ion gap(SIG)generated by the third generation equa-tion following pH and the anion gap(AG)in critically ill patients.Methods On the basis of the determination results of blood gas and blood biochemistry,the equation in the Stewart-Figge methodology was adopted to calculate SIG.Results (1)There were sta-tistically significant differences in K+ ,Na+ ,HCO3 - ,AG,pH,PO4 3 - ,ALB,SIG and Cr between the critical illness groups and the control group(P 〈0.05).(2)The SIG mean value ratio the death group to non-death group was 3.04,the difference was the big-gest,P 〈0.05,AG and Cr took the second place.Conclusion SIG as a new indicator in combination with other biochemical and blood gas indicators,such as the HCO3 - ,AG,pH,PO4 3 - ,Cr and lactic acid can reflect the situation of the acid-base disorders in critically ill patients and plays a strong indicative role in predicting the disease development trends. |
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Keywords: | strong ion gap intensive care units blood gas analysis lactic acid |
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