银川市12~17岁儿童青少年肌肉质量指数和心血管危险因素聚集的关系

  目的  探索儿童青少年肌肉质量指数(muscle mass index, MMI)与心血管危险因素(cardiovascular risk factors, CVRFs)聚集的关系, 为儿童青少年心血管疾病的防治提供科学依据。  方法  采用现况研究设计, 以整群随机抽样的方法抽取银川市12~17岁1 622名儿童青少年, 运用问卷调查、体格检查、体成分测定和实验室指标检测进行调查分析。  结果  未调整其他变量时, MMI与心血管危险因素聚集呈正相关(P值均 < 0.01), 调整年龄、性别和体质量指数(BMI)后, MMI与CVRFs≥1呈负相关(OR=0.74, 95%CI=0.62~0.89)。总人群中, 相比于MMI不足, MMI良好及充足与CVRFs≥1的发生风险呈负相关(OR=0.60, 95%CI=0.46~0.79;OR=0.56, 95%CI=0.37~0.85), 与CVRFs≥2的发生风险呈负相关(OR=0.54, 95%CI=0.37~0.79;OR=0.51, 95%CI=0.30~0.87), 男生中也有相似的结果(P值均 < 0.05)。  结论  相同BMI水平下, 肌肉质量指数是儿童青少年心血管危险因素聚集的保护因素。应重视儿童青少年体育锻炼, 保持最佳肌肉质量和体重。

Relationship between the muscle mass index and the aggregation of cardiovascular risk factors in children and adolescents aged 12-17 years in Yinchuan City

  Objective  To explore the relationship between the muscle mass index (MMI) and the aggregation of cardiovascular risk factors (CVRFs) in children and adolescents, and to provide a scientific basis for the prevention and treatment of cardiovascular diseases in children and adolescents.  Methods  The current situation study design was adopted, and 1 622 children and adolescents aged 12-17 years old in Yinchuan City were selected by a cluster random sampling method. All subjects were subjected to questionnaire survey, physical examination, body composition determination and laboratory index testing.  Results  When other variables were not adjusted, MMI was a risk factor for the aggregation of cardiovascular risk factors (P < 0.01). After adjusting for age, gender and BMI, MMI became a protective factor for CVRFs≥1 (OR=0.74, 95%CI=0.62-0.89), compared with insufficient MMI, the risk of developing CVRFs≥1 with good MMI and sufficient MMI was 0.60(95%CI=0.46-0.79), 0.56(95%CI=0.37-0.85) times. The risk of CVRFs≥2 was 0.54(95%CI=0.37-0.79), 0.51(95%CI=0.30-0.87) times, and similar results were found in boys (P < 0.05).  Conclusion  Under the same BMI level, muscle mass index is a protective factor for cardiovascular risk factor aggregation in children and adolescents. Physical exercise of children and adolescents should be emphasized to maintain the best muscle mass and weight.