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检测脑脊液诊断结核性和病毒性脑膜炎
引用本文:邱丽华,王学东,刘国利,孙吉昌,王春燕.检测脑脊液诊断结核性和病毒性脑膜炎[J].泰山医学院学报,2003,24(3):238-239.
作者姓名:邱丽华  王学东  刘国利  孙吉昌  王春燕
作者单位:山东省胸科医院,山东,济南,250013
摘    要:目的 研究脑脊液(CSF)结核抗体(PPD-IgG)、腺苷脱氨酶(ADA)、脑脊液糖与血糖比值在鉴别诊断结核性与病毒性脑膜炎方面的应用价值。方法 对156例结核性脑膜炎,42例病毒性脑膜炎患者脑脊液PPD-IgG、ADA、脑脊液糖与血糖比值的检测结果进行回顾性对比研究。结果 脑脊液PPD-IgG、ADA、脑脊液糖与血糖比值三者对诊断结核性脑膜炎的敏感性分别为84.6%(132/156)、95.5%(149/156)、97.4%(152/156);特异性分别为100%、71.4%和92.9%。结论 脑脊液PPD-IgG、ADA、脑脊液糖与血糖的比值对鉴别诊断结核性与病毒性脑膜炎具有重要的参考价值。

关 键 词:脑脊液  结核抗体  腺苷脱氨酶  脑脊液糖与血糖比值  结核性脑膜炎  病毒性脑膜炎
文章编号:1004-7115(2003)03-0238-02
修稿时间:2003年3月16日

Detection of PPD-IgG、ADA、and CSF-blood glucose ratio for differential diagnosis of tuberculosis and viral meningitis
QIU Li hua,WANG Xue dong,LIU Guo li,SUN Ji chang,WANG Chun yan.Detection of PPD-IgG、ADA、and CSF-blood glucose ratio for differential diagnosis of tuberculosis and viral meningitis[J].Journal of Taishan Medical College,2003,24(3):238-239.
Authors:QIU Li hua  WANG Xue dong  LIU Guo li  SUN Ji chang  WANG Chun yan
Abstract:Objective: To study the applied value of PPD IgG?ADA in CSF and CSF blood glucose ratio for differential diagnosis of tuberculosis and viral meningitis. Methods:156 patients with tuberculosis and 42 patients with viral meningitis were analyzed respectively.The PPD IgG?ADA of CSF and CSF blood glucose ratio were compared respectively. Result: The sensitivities of PPD IgG, ADA in CSF and CSF blood glucose ratio for diagnosis of tuberculosis meningitis were respectively 84 6%(132/156), 95 5%(149/156) and 97 4%(152/156).The specificities of them were respectively 100%, 71 4% and 92 9%. Conclusion: The PPD IgG, ADA in CSF and CSF blood glucose ratio are good indexes for differential diagnosis of tuberculosis and viral meningitis.
Keywords:cerebrospinal fluid PPD  IgG adenosine deaminase (ADA)  CSF  blood glucose ratio  tuberculosis and viral meningitis
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